Background:
@EN Since the introduction of antimicrobial agents, considerable changes have been taken place regarding the microbiologic patterns of bacteremia. Gram negative bacteriae have largely been replaced in this role with Staphylococci. Especially when
caused
by methicillin-resistant Staphylococcus aureus(MRSA) strains, S. aureus bacteremia is serious medical problem in association with high morbidity and mortality.
@ES Methods:
@EN In this retrospective study, we analysed 102 patients with S. aureus bacteremia who were admitted in the Korea University Guro Hospital over 6 year period. to evaluate risk factors of S. aureus bacteremia related to death and compare clinical
features of MRSA bacteremia with those of MSSA bacteremia.
@ES Results:
@EN 1) The case fatality rate for patients wtih S. aureus bacteremia was 31%, and thcse for MRSA and MSSA bacteremia were 55% and 20%, respectively.
2) The risk factors associated with MRSA bacteremia were the serious underlying diseases, previous use of antibiotics, steroids, various invasive procedures, and low serum albumin levels.
3) The risk facters that attributed to the increment of mortality rate in patients with S. aureus bacteremia were the high blood glucose, low serum albumin, various invasive procedures, hospital-acquired infection, respiratory tract infection as
a
primary focus, MRSA infection.
@ES Conclusion:
@EN Risk facors of fatal outcome in patients with S. aureus bacteremia were, low serum albumin, MRSA infection, high blood glucose by multivariate analysis in our study.
In addition, MRSA bacteremia was more frequent in patients with hospital-acquired infection, various invasive procedures, previous use of antibiotics, steroids and lowserum albumin.
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